AN UNUSUAL CASE OF PENILE TUMOR: GIANT SIZED VERRUCIFORM XANTHOMA OF PENIS

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Published 2023-01-10
Aditya Yogarama Josep Joko Hendratno

Abstract

Objective: This study aims to present a case of Verruciform Xanthoma (VX) on penile shaft. Case(s) Presentation: A 60 years old man was admitted to our hospital with a large sized (8cm) cauliflower like tumor on his penile shaft which started to appear 2 years prior to hospital admission. The tumor was continuously getting bigger during that period. The man did not feel any other signs and symptoms. Incision biopsy sample was taken and the histopathologic result was Verruciform Xanthoma. Then the patient took excision circumcision surgery. Discussion: Penile VX is a benign, asymptomatic, warty lesion that can occur in penile shaft, glans, coronal sulcus, and preputium. Its pathological mechanism is still unclear but the most accepted theories are mucocutaneous reaction to localized trauma and chronic inflammation. Due to its atypical appearance, it can be mistaken as other lesion, even a malignant one. Histopathological examination must be done to confirm diagnosis, and to plan the right treatment. We conduct excision and circumcision to compensate a wide skin loss and achieved satisfactory result. Conclusion: Penile VX can be mistaken as a malignant lesion, thus histopathological examination must be done to avoid over radical treatment. Excision and circumcision surgery for large sized penile VX achieve satisfactory result. Keywords: Penile, verruciform xanthoma, tumor.


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Keywords

Penile, verruciform xanthoma, tumor

References

Stiff KM, Cohen PR. Vegas (Verruciform Genital-Associated) Xanthoma: A Comprehensive Literature Review. Dermatol Ther Heidelb. 2017; 7: 65–79.

De Rose AF, Tosi M, Mantica G. Piol N, Toncini C, Terrone C. Verruciform Xanthoma of the Penis: A Rare Benign Lesion That Simulates Carcinoma. Archivio Italiano di Urologia e Andrologia. 2016; 88: 4.

Kobaner GB, Demir O, Ozturk Sari S, Baykal C, Buyukbabani N. Verruciform xanthoma of the penis: A rare case with an unusual clinical morphology. Indian J Dermatol Venereol Leprol. 2018; 84: 600-2.

Kraemer BB, Schmidt WA, Foucar E, Rosen T. Verruciform xanthoma of the penis. Arch Dermatol. 1981; 117: 516-518.

Shafer WG. Verruciform Xanthoma. Oral Surg. 1971; 31(6): 784-9.

Wang G, Mochel MC, Randall MB, Gandhi JS, Udager AM, Chan MP, Patel RM, Amin MB, Osunkoya AO, Smith SC. Genital Verruciform Xanthoma: Lessons from a Contemporary Multi-institutional Series. Histopathology. 2020; 77(5): 841-6.

Chan MP. Verruciform and Condyloma-like Squamous Proliferations in the Anogenital Region. Arch Pathol Lab Med. 2018: 1-11.

Cumberland L, Dana A, Resh B, Fitzpatrick J, Goldenberg G. Verruciform Xanthoma in the Setting of Cutaneous Trauma and Chronic Inflammation: Report of a Patient and a Brief Review of the Literature. J Cutan Pathol. 2010; 37: 895–900.

Qian A, Zhang L, Gao XH, Zheng S. Images of the month: Verruciform xanthoma: An Easily Confused Disease. Royal College of Physicians. 2020; 20(4): e123-4.

Cuozzo DW, Vaccher P, Sau P, Frishberg DP, James WD. Verruciform Xanthoma: A Benign Penile Growth. American Urological Association: The Journal of Urology. 1995; 153: 1625-7.

Sette CS, Wachholz PA, Brandão LSG, Marques GF, Casafus FS, Soares CT. Verruciform Xanthoma on the Penis: An Unusual Location. Clin Exp Dermatol. 2015. 40: 807-8.

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Department of Urology, Faculty of Medicine/Airlangga University