THE EFFECTIVENESS OF RENALOF® COMPARED TO KALKURENAL® AND PLACEBO

Benny Kristyantoro, Sabilal Alif, Tarmono Djojodimedjo, Budiono Budiono

Abstract


Objective: To compare the effectiveness after administration of Renalof to Kalkurenal and placebo in patient with renal calculus. Material & Method: We analyzed 30 patient with renal calculi less than or equal to 20 mm (2 cm) between January 2011 and March 2011. Patients were divided into 3 groups. Nine patients were treated with placebo, 8 patients were treated with Kalkurenal and the last 13 patients were treated with Renalof. After 30 days, we analyzed calcium and uric acid excretion for 24 hours and measured the stone with plain abdominal film and renal ultrasound. Results: There were decreased in excretion of calcium and uric acid all of patients but not significant statistically (p > 0,05) and there were significant decreased on stone measurement in patient treated with Renalof. Conclusion: Renalof  can be given as adjunct therapy for patient with renal calculi.
Keywords: Calcium and uric acid excretion in urine 24 hours, stone measurement and stone surface area.

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References


Stoller ML, Bolton DM. Urinary stone disease etiology, diagnosis and management. In: Tanagho EA and McAninch JW. 14th ed. Smith’s General Urology. 1995; 276-300.

Menon M, Resnick MI. Urinary lithiasis: Etiology, diagnosis and medical management. In: Campbell MF, Walsh PC, Retik AB, Vaughan ED, Wein AJ. 8th ed. WB Saunders. Campbell’s Urology. 1998; 3: 2662-94.

Rochani S. Guideline penatalaksanaan penyakit batu saluran kemih. 2007. p. 1-45.

Soebadi, DM. Laporan Tahunan 2005. Surabaya: Bagian Urologi RSU Dr. Soetomo - FK Unair; 2006.

Wolf JS. Nephrolithiasis. http://emedicine.medscape.com.2010

Lotan Y. Economic and cost of care of stone disease. Journal of the National Kidney Foundation. 2009; 16(1): 5.

Worcester EM, Coe FL. Cinical practice: Calcium kidney stone. N Engl J Med. 2010; 363: 954-63.

Munver R, Preminger JM. Urinary tract stone. In: Weiss RM, George NJR, O’Reilly PH. Comprehensive Urology. London: Mosby International Limited; 2001. p. 313-23.

Craig S. Renal calcul. 2010. www.emedicine.medscape.com

Pietrow PK, Karellas ME. Medical management of common urinary calculi. America Family Physician. 2006; 74(1): 86-94.

Wibisono. Karakteristik pasien batu ginjal di RSU Dr. Soetomo Januari 2007-Desember 2009. Surabaya: Bagian Urologi RSU Dr Soetomo-FK Unair; 2010.

Miller NL. Management of kidney stone. BMJ. 2007. p. 334.

Osman MM, Alfano Y, Kamp S, Haecker A, Alken P, Michel MS, et al. 5 years follow up of patients with clinically insignificant residual fragment after extracorporeal shockwave lithotripsy. European Urology. 2005; 47: 860-4.

Tan YH, Wong M. How significant are clinically insignificant residual fragments following lithotripsy? Curr Opin Urol. 2005; 15: 127-31.

Tracy CR, Pearle MS. Update on the medical management of stone disease. Current Opinion in Urology. 2009; 9(2): 200-4.


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