CHANGES IN ERECTILE FUNCTION BEFORE AND AFTER PROSTATE BIOPSY
##plugins.themes.bootstrap3.article.main##
##plugins.themes.bootstrap3.article.sidebar##
Abstract
Objective: To evaluate erectile function before and after transrectal ultrasound (TRUS) guided prostate biopsy using International Index of Erectile Function-5 (IIEF-5) and Erection Hardness Score (EHS) instrument. Material & Method: We conducted a study on 17 BPH LUTS patients who underwent TRUS guided prostate biopsy from January to April 2011 in Urological Minimal Invasive Installation (IIU) Dr. Soetomo Hospital. Out of 17 patients, three patients had mild ED, while 14 other patients had normal erectile function before the procedure. After TRUS guided prostate biopsy, we performed erectile function assessment using the IIEF-5 and EHS at weeks I, II, and IV. Results: Pathological examination of all specimens from prostate biopsy results revealed BPH. There were 2 patients with hematuria and 1 patient with rectal bleeding shortly after the biopsy, which resolved spontaneously less than 24 hours. Based on the IIEF-5 there were 4 patients (23,5%) with decreased erectile function in the evaluation of first week after prostate biopsy, and it reduced to 2 patients (11,7%) whose erectile function was still decreasing in the evaluation week II, while in fourth week evaluation there was 1 patient (5,9%) with decreased erectile function. Based on EHS data obtained, there were 5 patients (29,4%) with decreased scores in evaluations week II, and in the evaluation of week IV there were no patients having erectile function problems compared with EHS data before prostate biopsy. Conclusion: TRUS guided prostate biopsy can have temporary effect on erectile function.Keywords: Erectile dysfunction, prostate biopsy, international index of erectile function-5, erection hardness score.
##plugins.themes.bootstrap3.article.details##
Feldman HA, Goldstein I, Krane RJ. Impotence and its medical and psychosocial correlates: Results of the Massachusetts Male Ageing Study. J Urol. 2004; 151(1): 54-61.
John J.Male Sexual Function, A guide to clinical management. 2nd ed. Elsevier: Philadelphia; 2006.
Lue TF. Erectile dysfunction. The new england journal of medicine. 2000; 155: 1802-13.
Presti JC.Neoplasms of the prostate gland. Smith’s General Urology. 16th ed. Lange Medical Books/Mc Graw-Hill: New York; 2004.
Kirby R, Lepor H.Evaluation and nonsurgical management of benign prostatehyperplasia.Campbell-Walsh Urology. 9th ed. WB Saunders-Elsevier: Philadelphia; 2007.
Shetty S.2008. Transrectal ultrasonography (TRUS) of the prostate, viewed 19 Oktober 2010. http:// www.emedicine.com.
Klein Eric A, Platz Elizabeth A.Epidemiology, etiology, and prevention of prostate cancer. Campbell-Walsh Urology. 9th ed. WB Saunders-Elsevier: Philadelphia; 2007.
Dai Bo, Ye Ding-wei, Kong Yun-Yi, Shen Yi-Jin, Wang Bo-Hua. Individualized prostate biopsy strategy for Chinese patients with different prostatespecific antigen levels. Asian J Androl. 2008; 10(2): 325-31.
Chen ME, Johnston DA, Tang Kuang, Babalan RJ, Troncoso P. Detailed mapping of prostate carcinoma foci, biopsy strategy implications. American Cancer Society. 2000; 54: 320-31.
Zisman, A, Leibovici, Kleinmann J. The impact of prostate biopsy on patient well-being: a prospective study of pain, anxiety and erectile dysfunction. The Journal of Urology. 2001; 165: 445-54.
Goldstein, I, Bushmakin, Cappelleri. The erection hardness score and its relationship to successful sexual intercourse. J Sex Med. 2008; 10: 2374-80.
Manuel DD. Erection hardness and satisfiction with rapid sildenafil dose escalation from 50 to 100 mg in men with erectile dysfunction. Rev Mex Urol. 2009; 69(4):135-42.
Mulhall Irwin G, Bushmakin, Kyle H. Validation of the erection hardness score. J Sex Med. 2007; 6: 1626-34.
Brosman SA. Erectile dysfunction. 2006. viewed 10 November 2010, http://www.emedicine.com.
Shabsigh R. Epidemiology of erectile dysfunction, Male Sexual Function: A Guide to Clinical Management. 2nd ed. Humana Press Inc; 2006. p. 47-57.
Mulhall J. Erectile dysfunction: Monitoring response to treatment in clinical practise- recommendation an international study panel. J Sex Med. 2008; 4: 448-64.
Klein T, Palisaar RJ, Holz A. The impact of prostate biopsy and perprostatic nerve block on erectile and voiding function: A Prospective Study. The Journal of Urology. 2010; 184: 1447-52.
Akbal C, Turker R, Tavukeu H. Erectile function in prostate cancer-free patients who underwent prostate saturation biopsy. European Urology. 2007; 53: 540-6.
Ramey JR, Halpern EJ. Ultrasonography and biopsy. Campbell-Walsh Urology. 9th ed. WB Saunders-Elsevier: Philadelphia; 2007.
Goldstein I, Lue TF, Padma NH, Rosen RC, Steers WD, Wicker PA. Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group. N Engl J Med. 1998; 338: 1397-404.
Kaminetsky JC, Depko AJ, Stroberg P. In men with erectile dysfunction, satisfaction with quality of erections correlates with erection hardness, treatment satisfaction, and emotional well-being. J Sex Med. 2008; 6: 800-8.
Kadioglu A, Grohmann W, Depko A. Quality of erection in men treated with flexible-dose sildenafil for erectile function: Multicenter trial with double blind, randomized, placebo-controlled phase and an open-label phase. J Sex Med; 2007. p. 1-9.