A MULTICENTER STUDY OF BENIGN PROSTATIC HYPERPLASIA PATIENTS UNDERGOING TRANSURETHRAL RESECTION OF THE PROSTATE IN INDONESIA: A DESCRIPTIVE ANALYSIS
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Abstract
Objective: The study aims to provide a detailed understanding of the patient demographics and clinical features associated with TURP procedures in several tertiary hospital in Indonesia. Material & Methods: This study is a descriptive cross-sectional study conducted at four provinces in Indonesia. Patient data were collected from January 2021 to December 2023, including all patients diagnosed with BPH and who underwent TURP. The data were analyzed using the Statistical Package for Social Sciences (SPSS) version 28.0 (SPSS Inc., Chicago, Illinois, USA). Results: A total of 812 patients met the inclusion criteria for the study. The highest number of patients undergoing TURP (Transurethral Resection of Prostate) was at Saiful Anwar General Hospital, with 287 patients. The average prostate volume across all patients was 57.6±20.6 ml with an IPP (Intravesical Prostatic Protrusion) of 13.0±5.2 ml. Diabetes Mellitus was the most common comorbidity among the patients, affecting 271 patients (33.3%). Urinary retention was the most frequent reason for patients undergoing TURP, affecting 664 patients (81.7%), followed by bladder stones, which affected 58 patients (7.1%). Conclusion: Advanced age and a history of smoking are the primary clinical features observed in BPH patients undergoing TURP in Indonesia. Additionally, urinary retention has been identified as the main indication for TURP procedures in these patients. Keywords: TURP, BPH, IPP.
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TURP, BPH, IPP.
Egan K. B. The Epidemiology of Benign Prostatic Hyperplasia Associated with Lower Urinary Tract Symptoms: Prevalence and Incident Rates. The Urologic Clinics of North America. 2016; 43(3): 289–297.
Prasetyo, Z.A., Budaya, T.N., & Daryanto, B. Characteristics of Benign Prostatic Hyperplasia (BPH) Patients Undergoing Transurethral Resection of the Prostate (TURP). Jurnal Kedokteran Brawijaya. 2021; 31(4).
Peng, Z. F., Zhou, J., Song, P., Yang, L. C., Yang, B., Ren, Z. J., Wang, L. C., Wei, Q., & Dong, Q. Retrospective analysis of the changes in the surgical treatment of benign prostatic hyperplasia during an 11-year period: a single-center experience. Asian Journal of Andrology. 2021; 23(3): 294–299.
Daryanto, B., Budaya, T.N., & Meiyanto, J.D. Short-Term Complications of Transurethral Resection of The Prostate Performed By Urology Resident In Educational Hospital: Characteristics And Determinant Factors. Indonesian Journal of Urology. 2024; 31(1): 30-33.
Madersbacher, S., Sampson, N., & Culig, Z. Pathophysiology of Benign Prostatic Hyperplasia and Benign Prostatic Enlargement: A Mini-Review. Gerontology. 2019; 65(5): 458–464.
GBD 2019 Benign Prostatic Hyperplasia Collaborators. The global, regional, and national burden of benign prostatic hyperplasia in 204 countries and territories from 2000 to 2019: a systematic analysis for the Global Burden of Disease Study 2019. The lancet. Healthy longevity. 2022; 3(11): e754–e776.
Xiong Y, Zhang Y, Li X, Qin F, Yuan J. The prevalence and associated factors of lower urinary tract symptoms suggestive of benign prostatic hyperplasia in aging males. Aging Male. 2021; 23(5): 1432–9. 2.
Khan A, Shaikh SU, Ali Rabiya, Ahmed SB. Age and Prostatic Volume: The Prognosis for Benign Prostatic Hyperplasia. Pakistan Journal of Medicine and Dentistry. 2023 May 10; 12(2): 23-28.
Gandhi J, Weissbart SJ, Kim AN, Joshi G, Kaplan SA, Khan SA. Clinical Considerations for Intravesical Prostatic Protrusion in the Evaluation and Management of Bladder Outlet Obstruction Secondary to Benign Prostatic Hyperplasia. Vol. 12, Current Urology. S. Karger AG; 2018. p. 6–12.
Ishak M, Myh E, Eriad Yunir P, Penulis K, Muhammad Ishak dr. Hubungan Intravesical Prostatic Protrusion (IPP) terhadap Perubahan International Prostate Symptoms Score (IPSS) pada Pasien Benign Prostatic Hyperplasia (BPH) yang Diterapi dengan Α1-Blocker di Kota Padang. Jurnal Ilmu Bedah Indonesia. 2021; 49.
Tjahjodjati, Soebadi DM, Umbas R, Mochtar CA, Daryanto B, Noegroho BS, et al. Panduan Penatalaksanaan Klinis Pembesaran Prostat Jinak. 2021.
Putri, F., Fariz, M. Evaluation of the Accuracy of the Use of Intravesical Prostatic Protrusion Degree as the Predictor of Benign Prostatic Hyperplasia Management. Journal of Medical Science. 2024; 18(1): 11-16.
Xin C, Fan H, Xie J, Hu J, Sun X, Liu Q. Impact of Diabetes Mellitus on Lower Urinary Tract Symptoms in Benign Prostatic Hyperplasia Patients: A Meta-Analysis. Frontiers in Endocrinology. Frontiers Media S.A. 2022; 12: 741-748.
Udoh EA, Usoro AJ, Essiet IU. Association between Diabetes Mellitus and Benign Prostatic Hyperplasia. SAS Journal of Surgery. 2022 Dec 7; 8(12): 763–7. 8.
Cornu JN, Gacci M, Hashim H, Herrmann TRW, Malde S, Netsch C, et al. EAU Guidelines on Non-Neurogenic Male Lower Urinary Tract Symptoms (LUTS). 2024.
Lin YH, Hou CP, Chen TH, et al. Is diabetes mellitus associated with clinical outcomes in aging males treated with transurethral resection of prostate for bladder outlet obstruction: implications from Taiwan Nationwide Population-Based Cohort Study. Clin Interv Aging. 2017; 12: 535-541.
Xu, H., Fu, S., Chen, Y., Chen, Q., Gu, M., & Wang, Z. Smoking habits and benign prostatic hyperplasia: A systematic review and meta-analysis of observational studies. Medicine. 2016; 95(32): e4565.
Stefanus D, Siregar S. Association of Lower Urinary Tract Symptoms and Benign Prostatic Enlargement in Patients with Hypertension. Majalah Kedokteran Bandung. 2023 Mar 30; 55(1).
Wang YB, Yang L, Deng YQ, Yan SY, Luo LS, Chen P, et al. Causal relationship between obesity, lifestyle factors and risk of benign prostatic hyperplasia: a univariable and multivariable Mendelian randomization study. J Transl Med. 2022 Dec 1; 20(1).
Lerner LB, Barry MJ, Anurag ;, Das K, Gandhi MC, Kaplan SA, et al. Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: AUA Guideline. 2023.
Fogaing C, Alsulihem A, Campeau L, Corcos J. Is early surgical treatment for benign prostatic hyperplasia preferable to prolonged medical therapy: Pros and cons. Medicina. 2021; 57: 368.